L-690488
L-690488 is a proagent of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor. L-690488 has more effective cell penetration than L-690330[1][2].
Product Specifications
CAS Number
142523-14-6
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-690488.html
Solubility
10 mM in DMSO
Smiles
CC(P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)(P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)OC1=CC=C(O)C=C1
Molecular Formula
C32H52O16P2
Molecular Weight
754.69
References & Citations
[1]Atack JR, et al. Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers. J Pharmacol Exp Ther. 1994 Jul;270 (1) :70-6.|[2]Chen X, et al. Stimulatory effect of lithium on glucose transport in rat adipocytes is not mediated by elevation of IP1. Am J Physiol. 1998 Aug;275 (2) :E272-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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