PT1
PT1 is an AMPKα1 activator that directly activates the inactive truncated forms of AMPKα1 monomers[1].
Product Specifications
CAS Number
[331002-70-1]
UNSPSC
12352005
Hazard Statement
H302
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pt1.html
Purity
99.13
Solubility
DMSO : 20.83 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC(NC(S/C2=C/C3=CC=C(C4=CC(C)=C(C)C=C4[N+]([O-])=O)O3)=NC2=O)=CC=C1Cl
Molecular Formula
C23H16ClN3O6S
Molecular Weight
497.91
Precautions
H302
References & Citations
[1]Pang T, et al. Small molecule antagonizes autoinhibition and activates AMP-activated protein kinase in cells. J Biol Chem. 2008 Jun 6;283 (23) :16051-60.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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