Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Carebastine-d5

Carebastine-d5 is the deuterium labeled Carebastine. Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2].

Product Specifications

CAS Number

1189661-02-6

UNSPSC

12352005

Target

Histamine Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Cancer; Endocrinology

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C=C1)C(C)(C)C(O)=O)CCCN(CC2)CCC2OC(C3=CC=CC=C3)C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H]

Molecular Formula

C32H32D5NO4

Molecular Weight

504.67

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]De Luisi A, et al. Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling. Eur Respir J. 2009 Oct;34 (4) :958-66.|[3]Zhao Y, et al. Carebastine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor. Clin Exp Dermatol. 2008 Nov;33 (6) :785-7.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

H1 Receptor

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

FKBP51 (FKBP5) (NM_004117) Human Over-expression Lysate
LY401331 100 µg

FKBP51 (FKBP5) (NM_004117) Human Over-expression Lysate

Sign In for Pricing
View Details
AMDHD1 Mouse Monoclonal Antibody [Clone ID: OTI5B5]
CF809949 100 µg

AMDHD1 Mouse Monoclonal Antibody [Clone ID: OTI5B5]

Sign In for Pricing
View Details
Recombinant Human Complement C5a Protein
PKSH031511 50 µg

Recombinant Human Complement C5a Protein

Sign In for Pricing
View Details
Calretinin / Calbindin 2 (Mesothelioma Marker) (CALB2/2603), CF488A conjugate, 0.1mg/mL
BNC882603-100 1x 100 µL

Calretinin / Calbindin 2 (Mesothelioma Marker) (CALB2/2603), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Transglutaminase 2 (TGM2) Mouse Monoclonal Antibody [Clone ID: OTI1A3]
CF809188 100 µg

Transglutaminase 2 (TGM2) Mouse Monoclonal Antibody [Clone ID: OTI1A3]

Sign In for Pricing
View Details
SOX2 (Transcription Factor) (SOX2/1791), CF740 conjugate, 0.1mg/mL
BNC741791-100 1x 100 µL

SOX2 (Transcription Factor) (SOX2/1791), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details