2′,2′-Difluorodeoxyuridine (Standard)
2′,2′-Difluorodeoxyuridine (Standard) is the analytical standard of 2′,2′-Difluorodeoxyuridine. This product is intended for research and analytical applications. 2’,2’-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine. 2’,2’-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro. 2’,2’-Difluorodeoxyuridine arrests cell cycle at the early S phase and induces apoptosis in cancer cells.
Product Specifications
CAS Number
114248-23-6
Product Name Alternative
DFdU (Standard) ; 2',2'-Difluoro-2'-deoxyuridine (Standard)
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; Drug Metabolite; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-2-difluorodeoxyuridine-standard.html
Purity
99.81
Smiles
O=C(N1)N([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)C=CC1=O
Molecular Formula
C9H10F2N2O5
Molecular Weight
264.18
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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