TASIN-30
TASIN-30 is an EBP inhibitor, with EC50 values of 0.097 μM for EBP competition and 50 μM for DHCR7 competition, respectively[1].
Product Specifications
CAS Number
[1678515-93-9]
UNSPSC
12352005
Target
APC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tasin-30.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=C(C)C=C(C)C=C1C)(N2CCC(CC2)NCCC(C)O)=O
Molecular Formula
C18H30N2O3S
Molecular Weight
354.51
References & Citations
[1]Panayotis C Theodoropoulos, et al. A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins. J Am Chem Soc. 2020 Apr 1;142 (13) :6128-6138.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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