Fenoverine (Standard)

Fenoverine (Standard) is the analytical standard of Fenoverine. This product is intended for research and analytical applications. Fenoverine (Spasmopriv) is an orally active and powerful anti-spasmodic drug. Fenoverine reduces calcium ion influx by suppressing voltage dependent calcium channels. Fenoverine has antiemetic, analgesic, and antidiarrheal effects. Fenoverine induces rhabdomyolysis. Fenoverine can be used to study smooth muscle overexcitation related conditions such as gastrointestinal spasms[1][2][3].

Product Specifications

CAS Number

[37561-27-6]

Product Name Alternative

Spasmopriv (Standard)

UNSPSC

12352005

Target

Calcium Channel; Reference Standards

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fenoverine-standard.html

Smiles

O=C(CN1CCN(CC1)CC2=CC=C3OCOC3=C2)N4C5=C(SC6=C4C=CC=C6)C=CC=C5

Molecular Formula

C26H25N3O3S

Molecular Weight

459.56

References & Citations

[1]J Mironneau, et al. Fenoverine inhibition of calcium channel currents in single smooth muscle cells from rat portal vein and myometrium. Br J Pharmacol. 1991 Sep;104 (1) :65-70. |[2]Chung-Wen Chen, et al. Rhabdomyolysis induced by fenoverine: a case report and literature review. Acta Neurol Taiwan. 2005 Sep;14 (3) :143-6.|[3]Hu OY, et al. Determination of fenoverine, a modulator of smooth muscle motility, in capsules and in human plasma: application to dosage form stability and a pilot study in humans. J Pharm Sci. 1992 Jan;81 (1) :91-3.