Limonin
Limonin inhibits HIV-1 with an EC50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin has antiviral and antitumor activities[1][2][4].
Product Specifications
CAS Number
1180-71-8
Product Name Alternative
Limonoic acid 3,19:16,17 dilactone
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Apoptosis; Cytochrome P450; Endogenous Metabolite; HIV; P-glycoprotein
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Limonin.html
Purity
99.38
Solubility
DMSO : 41.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1[C@@H]2[C@@]3(O2)[C@](CC[C@@]([C@@]4([C@@](CC(OC4)=O)([H])OC5(C)C)[C@@]5([H])CC6=O)([H])[C@]36C)(C)[C@H](C7=COC=C7)O1
Molecular Formula
C26H30O8
Molecular Weight
470.51
Precautions
H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HIV-1
Available Sizes
Frequently Asked Questions
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