MSOP

MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR.

Product Specifications

CAS Number

[66515-29-5]

UNSPSC

12352211

Hazard Statement

H301

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/MSOP.html

Purity

98.0

Solubility

H2O : 62.5 mg/mL (ultrasonic)

Smiles

NC(COP(O)(O)=O)(C)C(O)=O

Molecular Formula

C4H10NO6P

Molecular Weight

199.10

Precautions

H301

References & Citations

[1]Thomas NK, et al. alpha-Methyl derivatives of serine-O-phosphate as novel, selective competitive metabotropic glutamate receptor antagonists. Neuropharmacology. 1996 Jun;35 (6) :637-42.|[2]Myron Yaster, et al. Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund’s adjuvant. Anesthesiology. 2011 Feb; 114 (2) : 412–423.