Neohelmanthicin A

Neohelmanthicin A (compound 3A) is a phenylpropanoid compound with antitumor activity. The IC50s of Neohelmanthicin A for inhibiting leukemia cell line EL4, breast cancer cell line S180 and breast cancer cell line MCF7 are 0.13 μM, 7 μM and 23 μM respectively[1].

Product Specifications

CAS Number

[920758-09-4]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/neohelmanthicin-a.html

Solubility

10 mM in DMSO

Smiles

C/C=C(C)\C(O[C@@H](C)[C@@](C)(O)C(O[C@@H](C)[C@@H](C1=CC(OC)=C(OCO2)C2=C1)OC(/C(C)=C\C)=O)=O)=O

Molecular Formula

C26H34O10

Molecular Weight

506.54

References & Citations

[1]Liu H, et al. Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica. Phytochemistry. 2006 Dec;67 (24) :2651-8.