Astilbin
Astilbin is a flavonoid compound and enhances NRF2 activation. Astilbin also suppresses TNF-α expression and NF-κB activation.
Product Specifications
CAS Number
29838-67-3
UNSPSC
12352005
Hazard Statement
H400
Target
Keap1-Nrf2; NF-κB; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Astilbin.html
Concentration
10mM
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1[C@@H]([C@@H](C2=CC(O)=C(O)C=C2)OC3=CC(O)=CC(O)=C13)O[C@@](O[C@@H](C)[C@H](O)[C@H]4O)([H])[C@@H]4O
Molecular Formula
C21H22O11
Molecular Weight
450.39
Precautions
H400
References & Citations
[1]Wang SW, et al. Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation. Food Chem Toxicol. 2018 Apr;114:227-236.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NF-κB; TNFRSF5/CD40
Available Sizes
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