Anti-Ramucirumab Polyclonal Antibody
Product Specifications
Background
Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells.
Product Name Alternative
Rabbit polyclonal to REGN-10987.
Host
Rabbit
Immunogen
Ramucirumab
Clonality
Polyclonal
Applications
ELISA
Purification
Antigen affinity purification.
Form
Liquid
Buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Storage Conditions
The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Notes
Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
Specificity
The product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays.
Isotype
IgG
Available Sizes
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