Anti-Eculizumab Polyclonal Antibody
Product Specifications
Background
Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.
Host
Rabbit
Immunogen
Eculizumab
Target
Rabbit polyclonal to Soliris.
Clonality
Polyclonal
Applications
ELISA
Purification
Purified by antigen affinity column.
Form
Liquid
Buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Storage Conditions
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Notes
Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
Specificity
The product is specific for Eculizumab. This antibody serves as an excellent positive control for Eculizumab immunogenicity (ADA) assays.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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