Dichlorophen

Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections[1][2].

Product Specifications

CAS Number

97-23-4

Product Name Alternative

DDM

UNSPSC

12352005

Hazard Statement

H302, H319, H410

Target

Bacterial; Fungal; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Dichlorophen.html

Concentration

10mM

Purity

98.55

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

Smiles

OC1=CC=C(Cl)C=C1CC2=CC(Cl)=CC=C2O

Molecular Formula

C13H10Cl2O2

Molecular Weight

269.12

Precautions

H302, H319, H410

References & Citations

[1]Kintz P, et al. Acute fatal poisoning with dichlorophen. Int J Legal Med. 1997;110 (2) :95-6.|[2]Khaw TH, et al. Identification of Bithionol, Dichlorophen, and Miconazole as Antibacterial Agents against Acinetobacter calcoaceticus. ACS Omega. 2020 Sep 8;5 (37) :23951-23959.