2-Bromo-2'-methoxyacetophenone
2-Bromo-2'-methoxyacetophenone is an irreversible inhibitor for MurA, that inhibits MurA in E. coli with an IC50 of 0.38 μM. 2-Bromo-2'-methoxyacetophenone can be used in antibacterial research for blocking bacterial cell wall synthesis[1].
Product Specifications
CAS Number
[31949-21-0]
Product Name Alternative
2-Bromo-1- (2-methoxyphenyl) ethanone
UNSPSC
12352101
Hazard Statement
H314, H318
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/2-bromo-2-methoxyacetophenone.html
Purity
99.43
Smiles
COC1=CC=CC=C1C(CBr)=O
Molecular Formula
C9H9BrO2
Molecular Weight
229.07
Precautions
H314, H318
References & Citations
[1]Mihalovits LM, et al., Catalytic Mechanism and Covalent Inhibition of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) : Implications to the Design of Novel Antibacterials. J Chem Inf Model. 2019 Dec 23;59 (12) :5161-5173.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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