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Elezanumab ELISA Kit

Product Specifications

Background

Elezanumab is a fully humanized monoclonal antibody directed against repulsive guidance molecule A (RGMa) . Studies in patients with multiple sclerosis (MS) demonstrate RGMa upregulation, which inhibits axonal growth and myelination, oligodendroglial regeneration and functional recovery after trauma or inflammation. Elezanumab treatment promoted axon regeneration, neuroprotection, remyelination, and immune modulation in several MS-relevant preclinical models. Elezanumab was previously well-tolerated as a single dose to healthy volunteers.

Specifications

Elezanumab

Product Name Alternative

ABT-555, AE12-1Y-QL (derived from parental mAb AE12-1 and AE12-1Y), CAS: 1791416-49-3

Detection Method

Colorimetric

Assay Type

Quantitative

Sample Type

Plasma, Serum

Detection Range

0.31-5 μg/mL

Recovery

80-120%

Sensitivity

0.156 μg/ml

Shipping Conditions

2-8 °C

Storage Conditions

The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Notes

For Research Use Only.

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