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Vorsetuzumab ELISA Kit

Product Specifications

Background

Vorsetuzumab mafodotin, also known as SGN-75, is a novel antibody conjugated with a cytotoxic molecule, auristatin analogue monomethyl auristatin phenylalanine (MMAF) . The antibody part of vorsetuzumab mafodotin is a monoclonal antibody targeting CD70, a member of CD70 tumor necrosis factor (TNF) superfamily. Vorsetuzumab mafodotin, developed by Seattle Genetics, has been used in the clinical treatment of Non-Hodgkin's lymphoma and renal cancer. This drug has completed a phase I clinical study in renal cell carcinoma but was discontinued in 2013. There were no reports specifying the reasons for the cessation of development. In 2014, SG had planned to reopen clinical studies related to vorsetuzumab mafodotin.

Specifications

Vorsetuzumab

Product Name Alternative

SGN-70, h1F6, SGN-75, CAS: 1165740-62-4

Detection Method

Colorimetric

Assay Type

Quantitative

Sample Type

Plasma, Serum

Detection Range

0.31-5 μg/mL

Recovery

80-120%

Sensitivity

0.156 μg/ml

Shipping Conditions

2-8 °C

Storage Conditions

The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Notes

For Research Use Only.

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