Ifabotuzumab ELISA Kit
Product Specifications
Background
Ifabotuzumab (formerly KB004) is a first-in-class therapeutic non-fucosylated IgG1 (human f-allotype) monoclonal antibody being developed by Humanigen (formerly KaloBios Pharmaceuticals) for the treatment of cancer. The drug was licensed from the Ludwig Institute for Cancer Research. The molecule contains a human antibody constant region with V-regions that are 92% identical to human germ-line sequences. Ifabotuzumab targets the ephrin type-A receptor 3 (EphA3) tyrosine kinase. In non-clinical studies, Ifabotuzumab demonstrated potent ex-vivo cell killing of EphA3+ tumor cells obtained from patients with hematologic malignancies.
Specifications
Ifabotuzumab
Product Name Alternative
Fibatuzumab, KB-004, , CAS: 1234137-51-9
Detection Method
Colorimetric
Assay Type
Quantitative
Sample Type
Plasma, Serum
Detection Range
0.31-5 μg/mL
Recovery
80-120%
Sensitivity
0.156 μg/ml
Shipping Conditions
2-8 °C
Storage Conditions
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Notes
For Research Use Only.
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