Vanucizumab ELISA Kit
Product Specifications
Background
Vanucizumab (RG7221) is an experimental humanized monoclonal antibody (mAb) designed for the treatment of cancer. Vanucizumab is a bi-specific mAb composed of two different heavy chains and two different light chains. One arm of the antibody binds Angiopoietin-2 (Ang2) and the other is based on bevacizumab (Avastin), binding vascular endothelial growth factor A (VEGF-A) . The antibody is designed to inhibit both VEGF-A and Ang2 simultaneously to offer superior clinical benefit compared to VEGF-A inhibition alone. This drug was developed by Genentech/Roche. On 12 Mar 2018, Roche completes a phase I trial in solid tumors (combination therapy, late-stage disease, metastatic disease, second-line therapy or greater) in Spain, France, and Belgium.
Product Name Alternative
RG-7221, RG7221, RO5520985, CAS: 1448221-05-3
Detection Method
Colorimetric
Assay Type
Quantitative
Sample Type
Plasma, Serum
Detection Range
0.31-5 μg/mL
Recovery
80-120 %
Sensitivity
0.156 μg/ml
Shipping Conditions
2-8 °C
Storage Conditions
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
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