11-O-Methylpseurotin A

11-O-Methylpseurotin A is a compound of mixed polyketide synthase–nonribosomal peptide synthetase (PKS/NRPS) origin. 11-O-Methylpseurotin A selectively inhibits a Hof1 deletion strain[1].

Product Specifications

CAS Number

[956904-34-0]

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Antibiotic; Bacterial; Complement System

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/11-o-methylpseurotin-a.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C)=C([C@@H](O)[C@@H](OC)/C=C\CC)O[C@]12C(N[C@@](OC)(C(C3=CC=CC=C3)=O)[C@@H]2O)=O

Molecular Formula

C23H27NO8

Molecular Weight

445.46

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Claudia M Boot, et al. Pinpointing pseurotins from a marine-derived Aspergillus as tools for chemical genetics using a synthetic lethality yeast screen. J Nat Prod. 2007 Oct;70 (10) :1672-5.