N-BOC-DL-serine methyl ester

N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α, β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity[1][2][3].

Product Specifications

CAS Number

[69942-12-7]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives

Type

Peptides

Related Pathways

Others

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-boc-dl-serine-methyl-ester.html

Purity

98.0

Solubility

DMSO : ≥ 200 mg/mL

Smiles

O=C(NC(CO)C(OC)=O)OC(C)(C)C

Molecular Formula

C9H17NO5

Molecular Weight

219.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Yang Yongqing, et al. Method for synthesizing α, β-dehydro-α-amino acid. Patent CN105037210. |[2]Wu Chengde, et al. Preparation of quinazolinone derivatives useful as PI3Kα inhibitors for the treatment of cancer. Patent WO2019091476. |[3]Pastor Fernandez, et al. Preparation of tricyclic pyrolopyranopyridines as protein kinase inhibitors. Patent WO2017033019.