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M-PEG5-CH2COOH

M-PEG5-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . m-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

16142-03-3

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/m-peg5-ch2cooh.html

Purity

99.90

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

OC(COCCOCCOCCOCCOCCOC)=O

Molecular Formula

C13H26O8

Molecular Weight

310.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Non-cleavable Linker; PEG Linkers

Available Sizes

Frequently Asked Questions

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