Senaparib
Senaparib (IMP4297) is a highly potent, selective and orally active PARP1/2 inhibitor. Senaparib (IMP4297) exhibits strong antitumor activity in animal models[1].
Product Specifications
CAS Number
1401682-78-7
Product Name Alternative
IMP4297; JS109
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/senaparib.html
Purity
99.53
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C(N1)N(CC2=CC=C(F)C(C(N3CCN(C4=NC=CC=N4)CC3)=O)=C2)C5=C(C(F)=CC=C5)C1=O
Molecular Formula
C24H20F2N6O3
Molecular Weight
478.45
References & Citations
[1]P. de Souza, et al. 574P Updated results of phase I study of senaparib (IMP4297) in Australian patients with advanced solid tumours. ABSTRACT ONLY| VOLUME 31, SUPPLEMENT 4, S490, SEPTEMBER 01, 2020.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PE/Cyanine5 Anti-Human IgM Antibody[MHM-88]](https://cdn.genprice.uk/products/763/68dd14ad061270361e7d33b5/imageurl/e-ab-f1172g.webp)
E-AB-F1172G-01 20 Tests
PE/Cyanine5 Anti-Human IgM Antibody[MHM-88]
Sign In for Pricing
View Details E-AB-F1172G-02 100 Tests
PE/Cyanine5 Anti-Human IgM Antibody[MHM-88]
Sign In for Pricing
View Details E-AB-F1172G-03 2x 100 Tests
PE/Cyanine5 Anti-Human IgM Antibody[MHM-88]
Sign In for Pricing
View Details 
BNC682616-500 1x 500 µL
Cadherin 17 / LI Cadherin (Liver-Intestine Marker) (CDH17/2616), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 