Research Grade Coltuximab
Coltuximabravtansine (SAR3419) isanantibody-drugconjugate (ADC) targetingCD19createdbyconjugatingaderivativeofthepotentmicrotubule-actingcytotoxicagent, maytansine, toaversionoftheanti-CD19antibody, anti-B4, thatwashumanizedasanIgG1byvariabledomainresurfacing.Fourdifferentlinker-maytansinoidconstructsweresynthesized (average∼3.5maytansinoids/antibodyforeach) toevaluatetheimpactoflinker-payloaddesignontheactivityofthemaytansinoid-ADCstargetingCD19.Anti-CD19humanizedmonoclonalantibodyconjugatedtoDM4.
Product Specifications
Product Name Alternative
SAR3419, CAS:1269764-99-9
Expression System
Mammalian Cells
Host
Chimeric
Target
CD19, DifferentiationantigenCD19, T-cellsurfaceantigenLeu-12, B-lymphocyteantigenCD19, B-lymphocytesurfaceantigenB4
Clonality
Monoclonal
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Purification
Protein A/G purified from cell culture supernatant.
Concentration
1mg/ml
Endotoxin
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Form
Liquid
Buffer
0.01M PBS, pH7.4.
Storage Conditions
Notes
For research use only. Not suitable for clinical or therapeutic use.
Buffer pH
0.01M PBS, pH7.4.
Species
Human
Isotype
IgG1-kappa
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Human CA 15-3 Matched Antibody Pair Set [Z01LS-0722-LS161]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
Human CA 15-3 Matched Antibody Pair Set [Z01LS-0722-LS161]
RBM10 (DXS8237E, GPATC9, GPATCH9, KIAA0122, RNA-binding Protein 10, G Patch Domain-containing Protein 9, RNA-binding Motif Protein 10, RNA-binding Protein S1-1, MGC1132, MGC997) (HRP)
RBM10 (DXS8237E, GPATC9, GPATCH9, KIAA0122, RNA-binding Protein 10, G Patch Domain-containing Protein 9, RNA-binding Motif Protein 10, RNA-binding Protein S1-1, MGC1132, MGC997) (HRP)