Complement System Alternative Pathway

The Wieslab® Complement System Alternative Pathway kit is an immunoassay for the qualitative determination of functional alternative complement pathway and determination of complement deficiencies in human serum. The Wieslab Complement assay combines the specific activation of the pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as the result of complement activation. The amount of C5b-9 generated is proportional to the functional activity of the complement system. The convenient ELISA technology has several advantages compared to the traditional hemolytic assays.