ST8 alpha-2,8-Sialyltransferase 6
ST8 alpha-2,8-Sialyltransferase 6 (ST8SIA6) is a sialyltransferase that generates α2,8-linked disialic acids, which bind to mouse Siglec-E and human Siglec-7 and -9, and accelerates tumor growth by suppressing anti-tumor immune responses[1].
Product Specifications
Product Name Alternative
ST8SIA6
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/st8-alpha-2-8-sialyltransferase-6.html
Solubility
10 mM in DMSO
Smiles
[ST8alpha-2,8-Sialyltransferase6]
References & Citations
[1]Friedman DJ, et al. ST8Sia6 Promotes Tumor Growth in Mice by Inhibiting Immune Responses. Cancer Immunol Res. 2021 Aug;9 (8) :952-966.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
20328064 1.0 µg DNA
FBXO34 Lentiviral Vector (Mouse) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details ![Mouse Monoclonal p120-catenin Antibody (OTI2E8) [Alexa Fluor 405]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-73179AF405 0.1 mL
Mouse Monoclonal p120-catenin Antibody (OTI2E8) [Alexa Fluor 405]
Sign In for Pricing
View Details 43734151 3x 1.0 µg DNA
SHROOM2 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Sign In for Pricing
View Details