ST8 alpha-2,8-Sialyltransferase 6
ST8 alpha-2,8-Sialyltransferase 6 (ST8SIA6) is a sialyltransferase that generates α2,8-linked disialic acids, which bind to mouse Siglec-E and human Siglec-7 and -9, and accelerates tumor growth by suppressing anti-tumor immune responses[1].
Product Specifications
Product Name Alternative
ST8SIA6
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/st8-alpha-2-8-sialyltransferase-6.html
Solubility
10 mM in DMSO
Smiles
[ST8alpha-2,8-Sialyltransferase6]
References & Citations
[1]Friedman DJ, et al. ST8Sia6 Promotes Tumor Growth in Mice by Inhibiting Immune Responses. Cancer Immunol Res. 2021 Aug;9 (8) :952-966.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
VP 771LD-5CS 1 Each
MAGNETIC BEAD SEPARATION PLATE, 96 Well, PCR Plate, V-Bottom, 24 Round Posts, 52MGO, NdFeB Magnets, Red Anodized Aluminum Magnet Frame, 1 Sided Pellet Location, 15-20ul Liquid Level, 7.9mm Post Diameter, Axial - North Poles Up Magnetic Orientation, Gripper Accessible, Step Down Edge for Full-Skirted Plates, 96 Chamfered Holes, SLAS Footprint, No Registration Base
Sign In for Pricing
View Details MBS7072033 Inquire
Recombinant Burkholderia ambifaria Lipoprotein signal peptidase (lspA), partial
Sign In for Pricing
View Details abx387926 96 Tests
Human Serine/Threonine-Protein Kinase ICK (ICK) ELISA Kit
Sign In for Pricing
View Details