ST8 alpha-2,8-Sialyltransferase 6
ST8 alpha-2,8-Sialyltransferase 6 (ST8SIA6) is a sialyltransferase that generates α2,8-linked disialic acids, which bind to mouse Siglec-E and human Siglec-7 and -9, and accelerates tumor growth by suppressing anti-tumor immune responses[1].
Product Specifications
Product Name Alternative
ST8SIA6
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/st8-alpha-2-8-sialyltransferase-6.html
Solubility
10 mM in DMSO
Smiles
[ST8alpha-2,8-Sialyltransferase6]
References & Citations
[1]Friedman DJ, et al. ST8Sia6 Promotes Tumor Growth in Mice by Inhibiting Immune Responses. Cancer Immunol Res. 2021 Aug;9 (8) :952-966.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Available Sizes
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