2-Deoxy-D-glucose-d1
Product Specifications
UNSPSC Description
2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
Target Antigen
Apoptosis; Hexokinase; HSV; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Apoptosis;Metabolic Enzyme/Protease;Others
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Solubility
H2O : 250 mg/mL (ultrasonic)
Smiles
O=C([2H])C[C@@H](O)[C@H](O)[C@H](O)CO
Molecular Weight
165.16
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.;Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r
Shipping Conditions
Room Temperature
Clinical Information
No Development Reported
CAS Number
188004-07-1
Available Sizes
Curated Selection
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