Recombinant Rat C1Inh protein (His tag)
Product Specifications
Background
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein
Abbreviation
C1Inh
Synonyms
C1 Inh; C1 esterase inhibitor; C1-inhibiting factor; C1Inh; Plasma protease C1 inhibitor; Serpin G1; Serping1
UniProt
Q6P734
Accession Number
Q6P734
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Ala504
Field of Research
Cardiovascular
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/ea1tad
Product MSDS
https://789.bio/eb/SGZaD8
Calculated Molecular Weight
55.3 kDa
Observed Molecular Weight
65 kDa
Species
Rat
Available Sizes
Curated Selection
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