Recombinant Rat C1Inh protein (His tag)

Product Specifications

Background

Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein

Abbreviation

C1Inh

Synonyms

C1 Inh; C1 esterase inhibitor; C1-inhibiting factor; C1Inh; Plasma protease C1 inhibitor; Serpin G1; Serping1

UniProt

Q6P734

Accession Number

Q6P734

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Ala504

Field of Research

Cardiovascular

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.