Recombinant Human AGT protein (His tag)
Product Specifications
Background
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Abbreviation
AGT
Synonyms
ANGT; ANHU; ANRT; AT-2; Aangiotensinogen; Alpha 1 antiproteinase antitrypsin; Ang; Angiotensin I; Angiotensin-3; PAT; SERPINA8; Serpin A8
UniProt
P01019
Accession Number
P01019
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Glu476
Field of Research
Signal Transduction; Cardiovascular; Cancer; metabolism
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
52.3 kDa
Observed Molecular Weight
60 kDa
Species
Human
Available Sizes
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