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Recombinant Human AGT protein (His tag)

Product Specifications

Background

Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Abbreviation

AGT

Synonyms

ANGT; ANHU; ANRT; AT-2; Aangiotensinogen; Alpha 1 antiproteinase antitrypsin; Ang; Angiotensin I; Angiotensin-3; PAT; SERPINA8; Serpin A8

UniProt

P01019

Accession Number

P01019

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Glu476

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Product Datasheet

https://cdn.gentaur.com/products/763/68dd1498061270361e7ce4e2/datasheet/pdmh100382.pdf

Product MSDS

https://789.bio/eb/te9pu5

Calculated Molecular Weight

52.3 kDa

Observed Molecular Weight

60 kDa

Species

Human

Available Sizes

Curated Selection

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