Recombinant Human LILRB3 protein (His tag)

Product Specifications

Background

May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM) .

Abbreviation

LILRB3

Synonyms

CD85 antigen-like family member A; CD85a; ILT-5; Immunoglobulin-like transcript 5; LIR-3; LIR3; Leukocyte immunoglobulin-like receptor 3; Monocyte inhibitory receptor HL9

UniProt

O75022

Accession Number

O75022

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Glu443

Field of Research

Immunology

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.