Recombinant Human LILRB3 protein (His tag)
Product Specifications
Background
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM) .
Abbreviation
LILRB3
Synonyms
CD85 antigen-like family member A; CD85a; ILT-5; Immunoglobulin-like transcript 5; LIR-3; LIR3; Leukocyte immunoglobulin-like receptor 3; Monocyte inhibitory receptor HL9
UniProt
O75022
Accession Number
O75022
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met1-Glu443
Field of Research
Immunology
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
46.1 kDa
Observed Molecular Weight
70 kDa
Species
Human
Available Sizes
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