Recombinant Human LILRB1 Protein (His Tag)
Product Specifications
Background
The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR) ) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR) . Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes, dendritic cells, and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.
Abbreviation
LILRB1
Synonyms
CD85 Antigen-Like Family Member J; CD85j; ILT-2; ILT2; Immunoglobulin-Like Transcript 2; LILRB1; LIR-1; Leukocyte Immunoglobulin-Like Receptor 1; Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; MIR-7; Monocyte/Macrophage Immunoglobulin-Like Receptor 7
UniProt
D9IDM8
Accession Number
D9IDM8
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gly24-His458
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/1khl0k
Product MSDS
https://789.bio/eb/pHl50O
Calculated Molecular Weight
48.2 kDa
Observed Molecular Weight
79 kDa
Species
Human
Available Sizes
Curated Selection
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