Recombinant Human LILRB1 Protein (His Tag)

Product Specifications

Background

The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR) ) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR) . Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes, dendritic cells, and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.

Abbreviation

LILRB1

Synonyms

CD85 Antigen-Like Family Member J; CD85j; ILT-2; ILT2; Immunoglobulin-Like Transcript 2; LILRB1; LIR-1; Leukocyte Immunoglobulin-Like Receptor 1; Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; MIR-7; Monocyte/Macrophage Immunoglobulin-Like Receptor 7

UniProt

D9IDM8

Accession Number

D9IDM8

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gly24-His458

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.