Recombinant Green monkey Calcitonin/CT protein (His tag)

Product Specifications

Background

Calcitonin (CT) is a protein hormones consist of 115aa with a disulfide bond. Calcitonin (CT) is most effectively produced by the parafollicular cells of the thyroid gland. It acts through the calcitonin receptor (CTR), a seven-transmembrane class II G-protein-coupled receptor linked to multiple signal transduction pathways with its main secretagogues being calcium and gastrin. Calcitonin regulates blood calcium levels and possesses certain clinically useful anti-fracture properties.

Abbreviation

Calcitonin; CT

Synonyms

CALCA; Calcitonin

UniProt

A0A0D9QXH0

Accession Number

A0A0D9QXH0

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala26-Asn140

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.