Recombinant rat PSMA / FOLH1 protein (His tag)
Product Specifications
Background
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate.
Abbreviation
PSMA; FOLH1
Synonyms
Folate hydrolase 1; Folh1; Folylpoly-gamma-glutamate carboxypeptidase (FGCP) ; Glutamate carboxypeptidase 2; Glutamate carboxypeptidase II (GCPII) ; Membrane glutamate carboxypeptidase (mGCP) ; N-acetylated-alpha-linked acidic dipeptidase I (NAALADase I)
UniProt
P70627
Accession Number
P70627
Expression System
E.coli
Tag
N-His
Sequence
Leu 471-Asp 750
Field of Research
Cancer; Metabolism; signal Transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
30.7 kDa
Observed Molecular Weight
30 kDa
Species
Rat
Available Sizes
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