Recombinant rat PSMA / FOLH1 protein (His tag)

Product Specifications

Background

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate.

Abbreviation

PSMA; FOLH1

Synonyms

Folate hydrolase 1; Folh1; Folylpoly-gamma-glutamate carboxypeptidase (FGCP) ; Glutamate carboxypeptidase 2; Glutamate carboxypeptidase II (GCPII) ; Membrane glutamate carboxypeptidase (mGCP) ; N-acetylated-alpha-linked acidic dipeptidase I (NAALADase I)

UniProt

P70627

Accession Number

P70627

Expression System

E.coli

Tag

N-His

Sequence

Leu 471-Asp 750

Field of Research

Cancer; Metabolism; signal Transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.