Recombinant Rat CD146/MCAM protein (His tag)
Product Specifications
Background
Melanomia Cell Adhesion Molecule (MCAM), also known as CD146 and MUC18, is a putative Ig-superfamily adhesion molecule that is expressed on endothelial cells and a variety of tumor cells. MCAM is associated with tumor progression and metastasis and may be involved in embryonic neural development. An alternately spliced isoform of rat MCAM has a 40 residue deletion in the cytoplasmic domain.
Abbreviation
CD146; MCAM
Synonyms
CD146; Cell surface glycoprotein MUC18; Gicerin; MUC18; Mcam; Melanoma cell adhesion molecule; Melanoma-associated antigen MUC18
UniProt
Q9EPF2
Accession Number
Q9EPF2
Expression System
E.coli
Tag
N-His
Sequence
His 151-Val 350
Field of Research
Cancer; Cardiovascular; Immunology; Signal Transduction; Stem Cells
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
21.9 kDa
Observed Molecular Weight
30 kDa
Species
Rat
Available Sizes
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