Recombinant Rat IL1A/IL-1F1 protein (His tag)

Product Specifications

Background

IL-1 alpha (Interleukin-1 alpha) is a cytokine that is induced during microbial exposure and promotes the release of multiple inflammatory mediators and acute phase proteins. It also supports hematopoietic stem cell expansion, promotes neutrophil mobilization from the bone marrow, and promotes osteoclast formation. IL-1 alpha signals through a receptor complex composed of IL-1 RI and IL-1 RAcP. It also binds the decoy receptor IL-1 RII which associates with IL-1 RAcP but does not transduce signaling.

Abbreviation

IL1A; IL-1F1

Synonyms

Interleukin; Hematopoietin; IL1F1hematopoietin; IL1F; IL-1F; alpha; BAF; Hematopoietin-1; IL1; IL1 alpha; IL-1 alpha; IL1-A; IL-1A; IL1-ALPHA; IL1F1; IL-1F1; IL1F1hematopoietin-1; interleukin 1; interleukin-1 alpha; LAF; LEM; preinterleukin 1 alpha; pro-interleukin-1-alpha; Il1a; FAF; Hematopoietin 1; IL 1 alpha; IL 1A; IL1; IL1 ALPHA; IL1F1; Interleukin 1 alpha; LAF; LEM; Preinterleukin 1 alpha; Il1a

UniProt

P16598

Accession Number

P16598

Expression System

E.coli

Tag

N-His

Sequence

Ser 115-Ser 270

Field of Research

Immunology; Metabolism; Neuroscience

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.