Recombinant Rat PAI-1/ SerpinE1 protein (His tag)
Product Specifications
Background
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
Abbreviation
PAI-1; SerpinE1
Synonyms
Endothelial plasminogen activator inhibitor; Mr1; Pai1; Planh1; Plasminogen activator inhibitor 1; Serpin E1
UniProt
P20961
Accession Number
P20961
Expression System
E.coli
Tag
N-His
Sequence
Ser 24-Pro 402
Field of Research
Cardiovascular; Cancer; Cell Biology; Metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
41.6 kDa
Observed Molecular Weight
42 kDa
Species
Rat
Available Sizes
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