Recombinant Rat PAI-1/ SerpinE1 protein (His tag)

Product Specifications

Background

Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.

Abbreviation

PAI-1; SerpinE1

Synonyms

Endothelial plasminogen activator inhibitor; Mr1; Pai1; Planh1; Plasminogen activator inhibitor 1; Serpin E1

UniProt

P20961

Accession Number

P20961

Expression System

E.coli

Tag

N-His

Sequence

Ser 24-Pro 402

Field of Research

Cardiovascular; Cancer; Cell Biology; Metabolism

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.