Recombinant Rat RUNX2/CBFA1 protein (His tag)
Product Specifications
Background
CBFA1, also called runt-related transcription factor 2 (RUNX2), is an essential transcription factor for the regulation of osteoblast differentiation. The CBFA1 gene potentially encodes several proteins that differ in their N-terminal sequences and transactivation capacities.
Abbreviation
RUNX2; CBFA1
Synonyms
Acute myeloid leukemia 3 protein; CBF-alpha-1; CBFA1; CCD1; CCDAML3; CLCD; ML3; OSF-2; OSF2; PEA2-alpha A; PEA2aA; PEBP2-alpha A; PEBP2aA; RUNX2; oncogene AML-3
UniProt
Q9Z2J9
Accession Number
Q9Z2J9
Expression System
E.coli
Tag
N-His
Sequence
Asp 127-Ile 218
Field of Research
Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology; Neuroscience
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
10.0 kDa
Observed Molecular Weight
12 kDa
Species
Rat
Available Sizes
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