Recombinant Rat RUNX2/CBFA1 protein (His tag)

Product Specifications

Background

CBFA1, also called runt-related transcription factor 2 (RUNX2), is an essential transcription factor for the regulation of osteoblast differentiation. The CBFA1 gene potentially encodes several proteins that differ in their N-terminal sequences and transactivation capacities.

Abbreviation

RUNX2; CBFA1

Synonyms

Acute myeloid leukemia 3 protein; CBF-alpha-1; CBFA1; CCD1; CCDAML3; CLCD; ML3; OSF-2; OSF2; PEA2-alpha A; PEA2aA; PEBP2-alpha A; PEBP2aA; RUNX2; oncogene AML-3

UniProt

Q9Z2J9

Accession Number

Q9Z2J9

Expression System

E.coli

Tag

N-His

Sequence

Asp 127-Ile 218

Field of Research

Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology; Neuroscience

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.