Recombinant Rat NT-proBNP protein (GST tag)
Product Specifications
Background
Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Likely involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, kaluresis and chloruresis
Abbreviation
NT-proBNP
Synonyms
ANFB_RAT; Brain natriuretic factor prohormone; Gamma-brain natriuretic peptide; Iso-ANP; Natriuretic peptides B; Nppb; preproBNP; proBNP
UniProt
P13205
Accession Number
P13205
Expression System
E.coli
Tag
N-GST
Sequence
His27-Arg76
Field of Research
Neuroscience
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
30.4 kDa
Observed Molecular Weight
30 kDa
Species
Rat
Available Sizes
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