Recombinant Rat KLK10 Protein (His Tag)

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Abbreviation

KLK10

Synonyms

Breast normal epithelial cell associated serine protease; KLK 10; KLK10; Kallikrein related peptidase 10; Kallikrein10; NES 1; NES1; Normal epithelial cell-specific 1; PRSS L1; PRSSL 1; PRSSL1; Protease serine like 1; Protease serine-like 1

UniProt

P36375

Accession Number

P36375-1

Expression System

E.coli

Tag

N-His

Sequence

Pro19-Pro259

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 85% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.