Recombinant Rat FGF2 Protein (His Tag)
Product Specifications
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Abbreviation
FGF2
Synonyms
BFGF; Basic fibroblast growth factor; Basic fibroblast growth factor bFGF; FGF 2; FGF B; FGF-2; FGF2; FGF2 basic; FGFB; Fgf2; Fibroblast growth factor; Fibroblast growth factor 2; Fibroblast growth factor 2 (basic) ; HBGF 2; HBGF-2; HBGF2; HBGH 2; HBGH2; Heparin bindi; basic
UniProt
P13109
Accession Number
P13109-1
Expression System
E.coli
Tag
N-His
Sequence
Pro10-Ala144
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/z1rtdk
Product MSDS
https://789.bio/eb/y540G8
Calculated Molecular Weight
15.2 kDa
Observed Molecular Weight
17.5 kDa
Species
Rat
Available Sizes
Curated Selection
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