Recombinant Gekko japonicus PDGFC protein (His tag)
Product Specifications
Background
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.
Abbreviation
PDGFC
Synonyms
Fallotein; PDGF-C; Platelet derived growth factor C; SCDGF; Secretory growth factor like protein; Spinal cord derived growth factor; VEGF E; VEGF-E
UniProt
A8WCC4
Accession Number
A8WCC4
Expression System
E.coli
Tag
N-His
Sequence
Asp 23-Gly 345
Field of Research
Cancer; Cardiovascular; Signal transduction; Stem cells
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
35.4 kDa
Observed Molecular Weight
40 kDa
Species
Gekko japonicus
Available Sizes
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