Recombinant Mouse CD20/MS4A1 protein (His tag)
Product Specifications
Background
CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa sequence identity between human and mouse CD20.
Abbreviation
CD20; MS4A1
Synonyms
B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; CD20; Lymphocyte antigen 44; Membrane-spanning 4-domains subfamily A member 1; Ms4a1
UniProt
P19437
Accession Number
P19437
Expression System
E.coli
Tag
N-His
Sequence
Leu 133-Pro 291
Field of Research
Cancer; Immunolegy; Neuroscience; Stem Cells; Epigenetics and Nuclear signaling.
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
17.4 kDa
Observed Molecular Weight
28 kDa
Species
Mouse
Available Sizes
Documents
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