Recombinant Mouse PGR protein (His tag)
Product Specifications
Background
Progesterone Receptor B (PR-B) is a 118 kDa member of the NR3 subfamily within the nuclear hormone receptor family of proteins. It is expressed in female reproductive tissues as well as neurons throughout the CNS. PR-B is particularly important in the mammary gland where it mediates proliferative responses to progesterone.
Abbreviation
PGR
Synonyms
Nuclear receptor subfamily 3 group C member 3; Pgr; Progesterone receptor
UniProt
Q00175
Accession Number
Q00175
Expression System
E.coli
Tag
N-His
Sequence
Ile 681-Lys 926
Field of Research
Cancer; Epigenetics and Nuclear signaling; Neuroscience; signal Transduction; Biochemicals
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
27.0 kDa
Observed Molecular Weight
30 kDa
Species
Mouse
Available Sizes
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