Recombinant Mouse IL-28B/IFN-lambda-3 protein (His tag)

Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Cytokine Zcyto; IL-12 subunit p; ZCYTO; Cytokine Zcyto22; Cytotoxic Lymphocyte Maturation Factor 35 kDa; IFNL4; IFN-Lambda-3; IFN-Lambda-4; IL-12 subunit p35; IL-12A; IL-28B; IL28C; IL-28C; Interferon Lambda-3; Interferon Lambda-4; Interleukin-12 subunit alpha; Interleukin-28B; Interleukin-28C; ZCYTO22; Il28; Il28b; Ifnl3

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.