Recombinant Mouse NFATc1 protein (His tag)
Product Specifications
Background
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.
Abbreviation
NFATc1
Synonyms
NF ATc1; NF Atc; NFAT2; NFATC 1; cytoplasmic 1
UniProt
O88942
Accession Number
O88942
Expression System
E.coli
Tag
N-His
Sequence
Pro 411-Ala 593
Field of Research
Immunology; Signal Transduction; Epigenetics and Nuclear Signaling
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
20.0 kDa
Observed Molecular Weight
23 kDa
Species
Mouse
Available Sizes
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