Recombinant Mouse INS protein (GST tag)
Product Specifications
Background
Insulin is a disulfide-linked heterodimeric protein secreted by the pancreatic Islets of Langerhans. Mature insulin is generated by the proteolytic removal of a peptide from proinsulin. It is involved in the regulation of glucose metabolism through interactions with the Insulin Receptor.
Abbreviation
INS
Synonyms
IDDM; IRDN; Ins-2; Insulin B chain; Proinsulin; ins
UniProt
P01326
Accession Number
P01326
Expression System
E.coli
Tag
N-GST
Sequence
Phe 25-Asn 110
Field of Research
Signal Transduction; Neuroscience; Cardiovascular; Metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
34.4 kDa
Observed Molecular Weight
30 kDa
Species
Mouse
Available Sizes
Documents
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